A new report presents DM-Seq (direct methylation sequencing), a bisulfite-free method for profiling 5-methylcytosine (5mC) at single-base resolution using nanogram quantities of DNA. The technique ...
Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...
DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...
In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models, or cultured cells.
Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...
Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...
A team of researchers from the Case Western Reserve University School of Medicine has developed a new method for target DNA sequence amplification, testing and analysis. This new technique, or ...
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