Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen that is often associated with healthcare settings but can cause serious infections in anyone. These illnesses are difficult ...

WITH our present knowledge of enzyme processes any conception of their mechanism must be essentially highly speculative. In the work under notice the author makes no claim to deal comprehensively with ...

Ten years ago, researchers obtained the first crystal structure of Dicer, a key enzyme in a biological process called RNA interference (RNAi). In RNAi, a process also known as gene silencing, a short ...

A new study led by scientists at IUPUI and Indiana University Bloomington is the first to describe a biochemical mechanism that increases the activity of a molecule whose presence is observed in many ...

An international research team has published a study in the journal The FEBS Journal that significantly advances the knowledge of a rare hereditary metabolic disease: classical homocystinuria. The ...

BUFFALO, N.Y. — In the human body, proteins called enzymes help speed up chemical reactions that are vital for life. After you eat, enzymes help your body break down food and obtain energy. Enzymes ...

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...

Metastatic melanoma is a deadly cancer for which conventional chemotherapy provides little benefit. However, newer therapies involving a pathway called the mitogen-activated protein kinase (MAPK) ...