Contrary to previous assumptions, nerve cells in the human neocortex are wired differently than in mice. The study found that human neurons communicate in one direction, while in mice, signals tend to ...

Researchers from the University of New Hampshire looked at the developmental process of the cerebral cortex—the outermost layer of the brain—and examined how neurons, or nerve cells, refine their ...

Alpha-synuclein (aSyn) is a highly conserved 140-amino acid presynaptic protein involved in neuronal plasticity and recognized as the pathogenic protein in Parkinson’s disease. Aggregated aSyn ...

Neocortical parvalbumin-expressing (PV) neurons critically regulate circuit excitation by strong synaptic inputs onto local pyramidal (Pyr) neurons. Plasticity in PV-mediated inhibition during ...

What makes us human? According to neurobiologists it is our neocortex. This outer layer of the brain is rich in neurons and lets us do abstract thinking, create art, and speak complex languages. An ...

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment, and the brain later in life, investigators at Johns Hopkins Medicine and ...

It has been known for nearly 20 years that slow, synchronous electrical waves in the brain during deep sleep support the formation of memories. Why that is, was previously unknown. How do permanent ...

Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...

After a decade out of the spotlight, the brain cells once alleged to explain empathy, autism and theory of mind are being refined and redefined. In the summer of 1991, the neuroscientist Vittorio ...

The brain may reuse some cells to store many different memories without mixing them up with or erasing older memories, a new study in mice suggests. Led by NYU Langone Health researchers, the study ...