The molecules in question are known as "nucleophiles" (literally, nucleus lovers), which share their electrons with "electrophiles" (literally, electron lovers) and serve as their atomic dance ...

The ability of covalent drugs to form strong bonds to protein targets tends to give them the advantage of long-lasting action. So far, covalent drug discovery has almost exclusively involved ...

As fantastic a nucleophile as fluoride is, when it’s tied up in an inorganic salt, such as CsF or KF, the anion becomes a recalcitrant reagent for organic synthesis because these salts are insoluble ...