Cilia are evolutionarily conserved microtubule-based organelles that project from the cell surface. In vertebrates, cilia are classified as motile or nonmotile (primary). Motile cilia often occur in ...
The NudC structure shows a conformation of a tight symmetric homodimer with the appearance of a butterfly with a wingspan of ∼70 Å and a height of 60 Å (Figure 1B). The dimer interface, which has an ...
Research in Focus is a series that highlights Neurobiology faculty members’ papers in peer-reviewed journals. A study led by Alecia K. Gross, Ph.D., professor and vice chair for Research and Research ...
The type I lissencephaly gene product USI, a key regulator of cytoplasmic dynein, is critical for cell proliferation, survival, and neuronal migration. However, little is known about the regulation of ...