Washington State University researchers have discovered how a neural circuit—or a connection between two brain regions—drives ...

Given how profound an influence opioids have on the world – for better or worse – scientists know surprisingly little about how these drugs actually work. A recent study led by researchers from ...

New research from a Max Planck Florida Institute for Neuroscience researcher could transform how we understand the way opioids affect the brain. Despite significant discussion surrounding the ongoing ...

Mapping how Narcan reverses opioid overdose can provide a molecular blueprint for developing more effective drugs against ...

Unbiased whole-brain mapping of c-Fos identifies active brain regions following a rewarding dose of oxycodone. c-Fos-positive cells are shown in red; white matter tracks are shown in green. Opioids, ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid receptors. What they didn't know—until now—was exactly what happens next. A ...

America remains in the grips of an opioid epidemic. Over the past 25 years or so, opioid overdose deaths have been rising steadily, reaching a record 81,806 in 2022, and not budging much since. Drugs ...

A new study published in Nature Medicine provides more evidence that ketamine’s rapid antidepressant effects may be partially dependent on the brain’s opioid system. The researchers found that ...

"This is your brain on drugs," the old anti-drug admonition says, and now a new study has found there's something to that chestnut. Opioid addicts experienced structural and functional changes in ...

Overdose deaths are a widespread problem North Carolinians have been struggling to combat in recent years. According to the state health department, American Indian/Indigenous and Black communities ...

Share on Pinterest Researchers say circuits in the brain could help provide pain relief without the use of opioids. Westend61/Getty Images Researchers have identified an alternative pain control ...