SN1 and SN2 reactions are fundamental types of nucleophilic substitution in organic chemistry, each with distinct mechanisms and characteristics. An SN1 reaction (Substitution Nucleophilic ...

A postfunctionalization strategy using blue LED light and an organophotoredox catalyst generates carbocation intermediates on polymer chains, enabling the incorporation of phosphonate esters. This ...

In the realm of reactivity, the vinyl carbocation is a beast so fleeting, so keen to combine or rearrange, that many have doubted that it can be tamed to create molecules in a stereoselective way. But ...

It is easier to form more substituted carbocations because of destabilisation in the parent substrate, rather than stabilisation in the reactive intermediate, new research shows. 1 Nearly 20 years ago ...

Human civilization in the 21st century is largely sustained by modern chemical technologies. The raw materials used in the manufacturing of a wide range of products, from clothing to plastics and ...

Chemists have coaxed vinyl cations to insert into C–H bonds of alkanes and arenes. In doing so, they’ve shown that this classic carbocation is capable of much more than previously thought. Although ...

The role of protonated cyclopropane (PCP +) structures in carbocation rearrangement is a decades-old topic that continues to confound. Here, quantum-chemical computations (PBE molecular dynamics, PBE ...

Aristolochene synthase, a metal-dependent sesquiterpene cyclase from Aspergillus terreus, catalyzes the ionization-dependent cyclization of farnesyl diphosphate (FPP) to form the bicyclic eremophilane ...