mTOR, mammalian target of rapamycin; p70S6K, The 70kDa ribosomal S6 kinase 1; NLRP3, NOD-like receptor thermal protein domain associated protein 3; ASC, apoptosis-associated speck-like protein ...

Significantly more patients with moderately to severely active ulcerative colitis achieved clinical remission with the investigational monoclonal antibody tulisokibart compared with placebo, a ...

New research has elucidated how an already identified area of the genome contributes to the development of a number of autoimmune or inflammatory diseases, including inflammatory bowel disease (IBD).

Scientists have shed light on how physical activity causes the cancer-fighting protein, interleukin-6 (IL-6), to be released into the bloodstream, thus helping repair the DNA of damaged cells. The ...

Most of the medications for constipation-predominant irritable bowel syndrome (IBS-C) are also used for chronic functional constipation, though there are some differences in how they’re used. In both ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...