Naloxone, the opioid overdose antidote, is a powerful tool in the overdose crisis, allowing friends, loved ones and even bystanders a way to put a fatal overdose in reverse and bring back breathing.

Washington State University researchers have discovered how a neural circuit—or a connection between two brain regions—drives ...

Given how profound an influence opioids have on the world – for better or worse – scientists know surprisingly little about how these drugs actually work. A recent study led by researchers from ...

Mapping how Narcan reverses opioid overdose can provide a molecular blueprint for developing more effective drugs against ...

New research from a Max Planck Florida Institute for Neuroscience researcher could transform how we understand the way opioids affect the brain. Despite significant discussion surrounding the ongoing ...

Overdose deaths are a widespread problem North Carolinians have been struggling to combat in recent years. According to the state health department, American Indian/Indigenous and Black communities ...

Unbiased whole-brain mapping of c-Fos identifies active brain regions following a rewarding dose of oxycodone. c-Fos-positive cells are shown in red; white matter tracks are shown in green. Opioids, ...

A new study published in Nature Medicine provides more evidence that ketamine’s rapid antidepressant effects may be partially dependent on the brain’s opioid system. The researchers found that ...

"This is your brain on drugs," the old anti-drug admonition says, and now a new study has found there's something to that chestnut. Opioid addicts experienced structural and functional changes in ...

Music can evoke intense pleasure, sometimes experienced physically as pleasant "chills." While the effect of music on pleasure is clear, the brain mechanisms behind musical enjoyment are not yet fully ...

Opioids are not stimulants. They are a class of medications primarily used for pain relief. Opioids and stimulants are two different classes of medications that address different needs. Doctors ...