South Florida vs UTSA Prediction, Odds, Picks - Nov. 6, 2025
Digest more
The Roadrunners travel to face USF looking to prove they can translate their Alamodome success to a road environment.
With McCown and his top targets, Devin McCuin and David Amador, growing healthier, the Roadrunners racked up a season-high 370 yards in a rout of Tulane.
The Green Wave are 5.5-point favorites in the latest Tulane vs. UTSA odds, while the over/under for total points scored is 54.5 via SportsLine consensus. Before making any UTSA vs. Tulane picks, check out the college football predictions from the SportsLine Projection Model .
Tulane head coach Jon Sumrall has been heavily linked to LSU this week. He was upset by a previously 3-4 team on Thursday night.
Still undefeated in American Conference play, Tulane hits the road for the first time in a month for what could be a shootout at the Alamodome.
What the analytics predict for Tulane vs. UTSA in this Week 10 college football game from an expert model that simulates games and projects scores.
The Tulane Green Wave do battle against the UTSA Roadrunners today in this exciting American Conference college football clash.
The University of Texas at San Antonio is planning to host the Lone Star State’s newest Division I football program to kick off its 2026 season.
UTSA head football coach Jeff Traylor had to set the record straight in his postgame press conference on Thursday night: the Roadrunners are not cheaters. It hasn't been the best season for UTSA, which is 4-4 so far and ranked eighth in the American Conference,